The Treatment of Intoxication with Ethynyl-Cyclohexyl Carbamate (ValmidR) by Extracorporeal Hemodialysis: A Case Report

Since the introduction of extracorporeal hemodialysis for the management of renal failure, its usefulness in the treatment of otherwise fatal poisoning by various chemical agents has been repeatedly demonstrated. Among these agents have been various barbiturates,' salicylates,' and bromide.' Recent experience with a case of intoxication with ethynyl-cyclohexyl carbamate (Fig. 1), a short-acting nonbarbiturate hypnotic,' provided an opportunity to demonstrate its dialyzability. Although the poisoning proved fatal in this instance, the ability to remove an appreciable quantity of the drug by hemodialysis suggests that patients with severe intoxication coming under observation earlier may be treated by this method more successfully.